Wie lange bleibt BetaBlocker (Medikamente) im Blut?
Hallo ich habe seit ca 10 Wochen eine Herzbeutelentzündung. Vor 2 Wochen hab ich mit meinem Arzt telefoniert und er meinte das ich die Medikamente für 2 Wochen ausschleichen und dann absetzten kann. Am Dienstag (14.3) habe ich meine letzte Tablette genommen.
Jetzt sind es 3 Tage ohne BetaBlocker her und mein Puls steigt wieder an nur beim laufen und stehen ist es sehr hoch
Laufen:107
Stehen:95
Jetzt habe ich plötzlich Schwindel und Kopfschmerzen bekommen. Man liest im Internet was von Entzugserscheinungen.
wie lange halten diese an und wann ist das Medikament aus meinem Blut?
Insgesamt habe ich nur die 1,25 mg genommen und beim ausschleichen dann jeden 2. Tag für 2Wochen genommen also von anfang an der Entzündung die geringste Dosis
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Bisoprolol is a β-receptor blocker that precisely blocks the β1 adreno receptors so that the signal transmission of blood pressure and heart rate-increasing transmitters impedes and thus lowers blood pressure and heart rate.
The half-life, i.e. the time until the active substance has been degraded half again, is 10-11 hours at bisoprolol. For the leaching time, i.e. the time until the active substance has been completely removed from the body, the half-life is calculated roughly five times. It is therefore necessary to expect 50-55 hours, i.e. a little more than 2 days, until at least no blood-mirror-induced effect is more noticeable. This, however, allows only a limited indication of when the actual settling symptoms decrease.
A short pharmacological trip for understanding: As with any active ingredient that blocks certain receptors, new receptors are also formed by the blockade. The effectiveness is based on the fact that more receptors are blocked than newly formed and this reaction does not compensate, but each receptor blocker subsequently encounters a new generation of new instances of the corresponding receptor.
If such an active substance is removed, the blockade of the receptors is removed relatively rapidly by degrading the active substance. The body can then react with the short-term recurrence of treated symptoms, because at this moment there is an oversupply of the corresponding receptors and therefore it increases sensitivity. However, the excess receptors form back again with time and the settling symptoms then generally disappear again.
Unfortunately, how long this takes is individual. If, however, you have to fight for longer than a few days with strong absorptive symptoms that do not leave noticeably, say again with your doctor.
Thank you so much for the washout time I didn’t know. I’ll wait a few days for a week.
It can be yours that my body has lived too much
Right, do that. Thank you very much.
If your heart muscle is not pre-damaged, the slipping out of the $ blockers will not be dangerous.
Good for you.
107 pulse frequency after sport are not problematic and a resting pulse of 95 can be found in the heart without diseases.
Don’t be crazy about it – it is important above all that after cardiac inflammation no permanent damage remains.
LA
Hey, so I had a Mrt on the 23.1 the diagnosis was delicate pericardial LGE, not a myocardial LGE. Found suitable for not acute, mild pericarditis.
Now my pulse always jumps from 70 to 90 and back
A minimal scar has remained on the heart bag due to inflammation. It’s completely harmless. The heart muscle itself is completely unfounded..
You don’t need to worry..
I have become extremely paranoid due to illness
The increased pulse, there can be the psyche of the trigger..
Your doctors are right, you can trust that. And the scarring is so minimal- hardly to prove.
I still have T1 and T2 mapping
The doctor says it’s not a scar.
You sure it’s a scar?
This disease has caused me extremely much stress and fear of death
Hi.
Betablockers are after approx. Completely degraded 20h, the half-life is 10-11h
LG
Harry
20h so fast?
So the symptoms are more likely to speak of withdrawal?
A half-life of 10-11 hours means nothing other than that the active substance is degraded to 75% after 20 hours.
This is what Mr rationalpharm has presented. :