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samm1917
5 months ago

Various drugs are used for the treatment of sleep disorders. Basically, the doctor decides what he writes to you and what does not, yet at this point a small overview:

Classic sleeping agents originate from the group of benzodiazepines (e.g. lorazepam, hallucinepam, midazolam etc.) and Z-drugs (Zolpidem and Zopiclon). They act highly effective, have close to no side effects, but make it difficult to rely on when used too frequently. Consequently, they serve primarily as emergency media for short-term use.

Other medicines are used for the longer term drug treatment of sleep disorders. Although these have a little less reliable and have more side effects, they do not depend. Concretely, the sleeping side effects of other drug groups are primarily utilized.

Antidepressants:

  • Mirtazapine (used very often)
  • Trazodon (usually well tolerated)
  • doxepine
  • trimipraminine
  • amolate
  • Amitriptylin (is rarely used for this purpose)

Antipsychotics:

  • Quetiapin (the non-retarded version is very often used)
  • promethazine
  • pipamperone
  • meperone
  • prothipendyl
  • levomepromazine

H1 antihistamines:

  • hydroxyzine
  • Diphenhydramine (lower but not subject to prescription)
  • Doxylamin (lower but not subject to prescription)

Orexin receptor antagonists:

  • Daridorexant: Daridorexant is a prescription very new and pure sleeping agent, which is usually very well tolerated, does not depend and does not cause a hangover on the following morning. Problem: It is very expensive.
samm1917
5 months ago
Reply to  erdnaandre

I read your post. If you ask me (but I’m not a doctor) your sleep disorders have become self-employed. You don’t go to bed with the expectations. This vicious circle must be broken. Since you are already looking at your sleeping hygiene, a medicamentary treatment (in my opinion) is quite an option.

You write that you had a hangover from Trimipramin. This is no longer surprising. Trimipramin has a half-life of about 24 hours. You therefore need a medicament which has a sleeping effect, does not make dependent, is compatible and has a short half-life. It’s not easy. Here may be some ideas:

  • Quetiapine is an atypical antipsychotic which is frequently used in low doses (about 25mg) in sleep disorders (the non-retarded version). As a rule, it is very effective and the side effects at this dosage can often be overlooked (but not always). The half-life is about 7 hours. Depending on the compatibility, a hang-over can occur or not. To find out this, you should try it.
  • daridorexant is an orexin receptor antagonist and thus a pure sleeping agent, which does not however make dependent. Daridorexant usually acts very reliably and is also very well tolerated. It’s not a hangover. The half-life is about 8 hours.
  • trazodone is an atypical antidepressant. The non-retarded version is frequently used for the treatment of sleep disorders and is generally well tolerated. It has a completely different mechanism of action than all other medicines (including antidepressants). The half-life is about 8 hours. A hangover can occur, but is not common.
samm1917
5 months ago

Ich bin kein Arzt und will deinem nicht zu nahe treten, doch Amitriptylin ist was das potenzial von Nebenwirkungen betrifft deutlich “krasser” als Quetiapin, Trazodon oder Daridorexant. Konkret:

Sehr häufige Nebenwirkungen bei Amitriptlyin (mehr als 10% aller Konsument*innen betroffen):

  • Schläfrigkeit/Benommenheit
  • Zittern der Hände oder anderer Körperteile
  • Schwindel
  • Kopfschmerzen
  • Herzklopfen, unregelmässiger oder schneller Herzschlag
  • Schwindelgefühl beim Aufstehen wegen niedrigem Blutdruck (orthostatische Hypotonie)
  • Mundtrockenheit
  • Verstopfung
  • Übelkeit
  • starkes Schwitzen
  • Gewichtszunahme
  • undeutliches oder langsames Sprechen
  • Aggression
  • verstopfte Nase

Sehr häufige Nebenwirkungen bei Quetiapin:

  • Schläfrigkeit
  • Gewichtszunahme
  • Schwindel
  • Kopfschmerzen
  • unwillkürliche Muskelkontraktionen oder unkontrollierte Muskelbewegungen Mundtrockenheit
  • Abnahme der Anzahl roter Blutkörperchen
  • hoher Blutzucker
  • Absetzsymptome bei abruptem Weglassen der Medikation

Sehr häufige Nebenwirkungen von Daridorexant:

  • keine

Sehr häufige Nebenwirkungen bei Trazodon:

  • Mundtrockenheit
  • Schläfrigkeit

Die Wirksamkeit ist von Person zu Person sehr unterschiedlich. Im Durchschnitt ist wohl Quetiapin am wirksamsten, gefolgt von Daridorexant. Dann Amitriptylin und am Ende Trazodon. Aber eben, jeder Mensch reagiert auf jedes Psychopharmakon etwas unterschiedlich.

samm1917
5 months ago

I’d do and listen to what he has to say. He can give you even more/more accurate information about these medications or he has other alternative suggestions.

Sarkasie
5 months ago

Hello Erdnaandre!

What sleep disorders: insomnia, sleep apnea, sleep or sleep, excessive daily fatigue….?

Is the cause known as stress, anxiety, depression, physical illness or unhealthy sleeping habits?

Because without diagnosis, no therapy!!

Many medicines can also be purchased without prescription. In sleep disorders, H1 receptor antagonists such as diphenhydramine doxylamin, cetirizin, Loratadin etc. are used. They have much less side effects than psychopharmacists.

Although most are well tolerated, they should only be taken in consultation with the doctor if the drug is suitable. Especially in the case of pre-disorders, taking without medical consultation may be associated with health risks.

Substances contained in formulations such as benzodiazepines or the similarly acting so-called. Z-substances such as Zopiclon, Zolpidem or Zaleplon. These act primarily anxious, scratching, muscle relaxant and damping. However, these can also lead to reduced drive, innocence, dizziness and a general emotional insufficiency. In addition, these substances have a high dependence potential. Therefore, these should be taken only in the short term and exclusively under medical supervision!

Psychopharmaceuticals often have the most common side effects than other common drugs.

The doctor usually prescribes prescription sleeping pills only if he considers it necessary. The use of such medicines is generally only advisable when all other measures such as sleep hygiene, medicinal plants or sleep dissection have been successful.

Greetings Sarkasie

Zawadie
5 months ago
Reply to  Sarkasie

👍😊

Sarkasie
5 months ago
Reply to  Zawadie

Thank you

Sarkasie
5 months ago

I’ll push the thumbs!

Sarkasie
5 months ago

Topics such as taking medications, interactions, (over) dosage and drug abuse are very critical here: Diagnosis, therapies and medication should only meet treating physicians and trained professionals.

I therefore turn out more generally.

Trimipramin belongs to the group of tricyclic antidepressants. It is primarily used to treat depression, but can also be used in anxiety disorders and sleep disorders. Trimipramin acts by inhibiting the resumption of neurotransmitters such as serotonin and norepinephrine in the brain, which can lead to an improvement in mood and alleviation of anxiety. As with many antidepressants, adverse side effects can also occur in the case of trimipramin, which is why medical monitoring is important during the treatment.

If you’ve already had good experiences with Trimipramin, as far as you’ve done, I’d try again. As I mentioned, you should finally come to rest at night, sleep for at least. Six hours. This could be a first step towards improvement;)

Sarkasie
5 months ago

I have been following the tip of getting out of bed insomnia and doing something until you get tired automatically…. Maybe it’s also an option to get used to sleepless critique.

In Turkey, a man has been living without sleep for 55 years. What do I have to keep up in bed at night?

🙈 Oh, no, that’s the wrong way you want to go.

There are some people who only need four hours of night sleep.

But 55 years without sleep, sounds superhuman for me and is also not a healthy example of generality, certainly just a single case.

I know an experiment for the longest time without sleep: 11 days 25 min. This record was set up in 1964 by Randy Gardner, a 17-year-old student.

But deliberate avoidance of sleep involves serious health risks and is not recommended!!

A healthy night sleep is therefore so important:

▪︎ Relaxation for the heart. Because fat and sugar metabolism is also regulated, the risk for HK diseases can be reduced.

▪︎ Sleep deficiency can make thick and negatively affect blood sugar levels, thus there is an increased risk for diabetes mellitus.

▪︎ The immune system, the defenses are strengthened.

▪︎ Night rest regulates hormone distribution and also plays an important role in metabolism and cell repair.

▪︎ Rest for body and mind. If you sleep well, you can better reduce stress. Who does not seem more susceptible to mood fluctuations and mental illnesses.

▪︎ Sleep strengthens memory. Those who hardly sleep are less absorbent the next day and can’t remember the information long.

An examination in the sleep laboratory helps to clarify sleep problems and diseases associated with sleep.

The HA or the treating FA transfers patients to the sleep laboratory. Such FÄ are, inter alia, HNO doctor, neurologist, psychiatrist or internist.

If you do the night to the day and vice versa, you’ll get your biological clock completely messed up. Very interesting I find the facts about the Chinese organ watch!

Look in here.

https://www.carstens-stiftung.de/artikel/die-chinesische-organuhr.html

Sarkasie
5 months ago

You are welcome

Sarkasie
5 months ago

The link somehow doesn’t work

Sarkasie
5 months ago

Ojee, your history of suffering I can feel well because I have problems with sleep too. With me, the problem is when I mainly take unresolved worries into sleep, then I sometimes inevitably grumble for hours and more. Long periods of wake in the night, so that I have too little sleep in total, and I’m like wheeled during the day, I find even worse than sleep disorders.

I keep hearing that many neuroleptics or even up to 11 antidepressants have already tried.

Or I read if someone is always disappointed in psychopharmacology. Since it had deteriorated in the course of the year, she thought, she gives all this a new chance, after two years of abstinence.

Many have actually only the desire to find a drug against their sleep disorders.

As a patient describes, at the beginning of the year was against his will in the psychiatry, he tried many neuroleptics, none worked. They make him tired, but not sleepy and the next day he has a huge overhang. Ultimately, only Zopiclon, which had to be quickly dropped.

Or that in a trimipramine helps as a sleeping agent and sleeping agent.

For example, if you go to a psychiatrist, you’ll come soon after his speech. with further diagnoses. Like a depression that is quickly treated with antidepressant. Depressive people often suffer from sleep disorders. In many cases, Mirtazapin is started. It often helps within 15 min, at the latest 30 min after taking. Then you really sleep like a baby. I took Mirtazapin’ smelting tablet. The dose is increased from time to time, as the effect is also quickly filled. Often, Mirtazapin is also happy to be combined with psychopharmacists.

If all this helps nothing, then there are other drugs with similar active ingredients. If you’re a serious case, you finally took 10 different medications as mentioned above. Many patients have to swallow more than just an antidepressant or neuroleptic. In addition, there are often also L-thyroxin, vitamin D, heart medications or insulin preparations.

I have a good video here for you with a psychotherapist:

What do antidepressants, neuroleptics and co? – My experiences with psychopharmacists

All right. 6:10 min he speaks specifically to sleep disorders.

http://www.https//m.youtube.com/watch?v=BBzgciBhEZg

What I remember is a diagnosis in the sleep laboratory. The waiting times should be very long. I was in the sleep laboratory Charité Berlin years ago, but without success.

SirSulas74
5 months ago

If antihistamines do not count, etc., this is the best. Melatonin doesn’t really help me. What’s better than the two are not without prescription.

Uh… yeah, I don’t know any prescriptions. Michael Jackson probably liked Propofol but died

DianaValesko
5 months ago

Your doctor can order you neuroleptics in the lowest dose, they work sleep-promoting and sleeping and not antidepressive in low dose, so they are prescribed to sleep.

You should ask if that would be suitable for you.

Good improvement for you.

DianaValesko
5 months ago
Reply to  erdnaandre

Neurocil drops, they are good to dose

DianaValesko
5 months ago
Reply to  erdnaandre

Trimipramin leads to weight gain when taking a lantern and has anticholinergic side effects.

You should talk to your prescribed doctor again, as your problem is wide-ranging.

hoermirzu
5 months ago

I sleep very well with lavender flowers and valerian’s root.

If I were more powerful, I asked my doctor to wake up again.

Gringo58
5 months ago
Reply to  erdnaandre

I took it yesterday and yesterday…Result = 0

AriZona04
5 months ago

Your sleep problems have at least one cause. Find them out and eliminate them. Enjoy a healthy lifestyle. Then you will also sleep in and through.

AriZona04
5 months ago
Reply to  erdnaandre

Yes. And I have no sleeping problems.

AriZona04
5 months ago

Do you live healthy: Do you eat sufficient and healthy? Are you drinking enough? Are you moving? Do you perform tasks during the day? If so, you will be happy to rest at night.

AriZona04
5 months ago

Do you know the causes of your insomnia?

Brutmudda
5 months ago

Try sports.

Brutmudda
5 months ago
Reply to  erdnaandre

Then you do something wrong or have an unhealthy lifestyle.

Brutmudda
5 months ago

It was too high for you, forget it.

Brutmudda
5 months ago

Well, if this happy lifestyle infiltrates health, you might want to turn to the lucky barometer so that you can have longer luck in the long term.

Brutmudda
5 months ago

What’s your lifestyle?