Warum tut es noch weh, weil Opa vor 2,5 gestorben ist?
Bei meinem Opa wurde 2011 Prostatakrebs im fortgeschrittenem Stadium festgestellt. Stadium T 3b pn1, M 0, V 1, L 1, R 1 und sie haben alles nicht erwischt und hatte Lymphknotenmetastasen, Samenblasenbefall. Er bekam 40 Strahleneinheiten und eine Hormontherapie Spritze Depot. Von 2011 bis 2014 war PSA immer 0,07 und ab 2015, 2016 schwankend 0,11, 0,10, 0,24, 0,07. 2017 steigte der PSA auf 1,83, 3,84, 8,54 und 2018 dann auf 14,48 und 24,45 und dann auf 98,86. Er musste zum MRT/CT und es gab mehrere vereinzelte Herde. Neben der AHT Antihormonterapie bekam er Zytika 250 mg und musste vier Tabletten täglich nehmen. Die Werte gingen runter bis auf 9,01. Ab 2021 hätte Opa Erleada bekommen, aber die hatte er nicht vertragen. Er konnte lang keine Stuhlgang machen und im KH wurde Enddarmkrebs festgestellt mit Bauchfellmetastasen und kann es sein das der Prostatakrebs auch in den Darm gestreut hatte?
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Cancer can sprinkle; once over the bloodstream, for example, to the liver, the brain or the bone, as well as via the lymph pathways. The lymph system is reached earlier than the bloodstream of the cancer cells, so that the metastases can form in the lymph nodes of the basin or outside.
Ok and then the prostate cancer was no longer curable by my grandpa?
If metastases have already formed, it is generally difficult; the cancer spreads; if the cancer remains locally it can be treated better or locally. This is the vicious of cancer. President Mitterand lived with the disease for almost 15 years.
If the cancer is discovered in time, there may be no metastases. These can, of course, already be present when the cancer had evolved a long time ago. Because the cancer can scatter and spread in the body, it is difficult to prevent it. Certainly, cancer therapy is better than 20 years ago, e.g., and will continue to improve. There are already laser therapy; it is commonly used for skin cancer.
Okay. 2011 was not yet a hint in the CT, 2014, but in 2018 there were several flocks (Metasen) available. Unfortunately no R0 diagnosis on my grandpa. I would have meant that metastases were created only before diagnosis and then no longer. When will cancer be cured in the final stage with metastases and not treated palliatively?
The R1 diagnosis certainly calculated that later metastases are formed. If it is possible to remove the original tumor completely, no metastases are created.
Okay, but that came later metastases. I have seen transfer from Opa 2021 and there was an increase in metastasis. Did he have metastases?
I didn’t mean any metastases yet; sorry.
Okay. There were no remote metastases yet, but stage T3b N1 M0, V1, L1, R 1. Opa had 40 irradiations and a hormone therapy depot syringe every three months. PSA 2011 to 2015 is still 0.07 stable, but from 2016 there were fluctuations and increases, but not yet strong. In 2017, stronger to 3, 6, 9 and 2018 to 14, 24, 98. In the CT 2018 they found several isolated herds. Follow Cytics tablets (hormone therapy) others.
As I understand it, there is no longer a residual tumour; of course, it could be later. As M0 stands above, there were probably still metastases in 2011, so they would have been born out of the residual tumor over time.
Okay, so would he have been completely cured at R0?
In practice, a residual tumor is no longer recognizable in R0; in R1, a remainder is then visible in the tissue sample. Resttumor . https://www.krebsinformationsdienst.de/studie/krebs-befunden-verstand.php
Okay, my grandpa couldn’t reach anything. R1 residual tumor on the edge of the cut. I read at R0 the cure is very high than at R1.
You loved your grandpa. And that’s why it hurts. This is completely normal
That’s right. He was my only reference person since birth, but he always wanted me to get a girlfriend who takes me as I am and he definitely gave me that