Do 2 in 1 laptops have a negative impact on working as a programmer?

Hey! Question: I'm starting my computer science degree next week and wanted to ask if anyone has experience with 2-in-1 laptops as a programmer or game developer. I'm interested in the HP Spectre 360X with 32GB and an RTX 4050. (They're currently having a great sale.) Question: I also do some rendering and video editing…