Scientists are still relatively uncertain about this. Some say it inhibits degradation, others say it has no effect at all, and still others say it intensifies the negative effects.
(1 votes)
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Didn’t know that science was insecure. I believe that Grapefruit consumption can have an impact on the effects of various medicines.
→ https://www.zentrum-der-gesundheit.de/bibliothek/medikamente/nebeneffekten-medikamente/grapefruit-und-medikamente
It is possible that the experience of some users deviate because more or less of the relevant active ingredients can be contained in grapefruit juice and/or the intake has not been well tampered.
It should be borne in mind that the side effects can almost necessarily increase with each active reinforcement. The experiment is to be guessed.
Thank you very much
Please, please.
In withdrawal clinics for “warm” opiate withdrawal and in substitution practices, it is possible to administer the respective agent together with (in) a sip of grapefruit juice, which, however, only happens for reasons of the excess taste of the substitute.
A reliable but individual response provides in such cases ordered and documented self-testing with predetermined doses at the same “exploratory conditions” as possible, such as gastric content, time of day and robust nature, for maintaining undesirable side effects.
Right. And ne dose narkanti,flumenizol, and other useful antidote 🤦
If you choose to travel round flights on such DXM-Semilegal-Substanz, you can ask for over-counted envelopes for small cents and leave Naloxon better for those who really need it.
There are kids who want to know, but they don’t want answers that don’t fit them into the drug limit test. They are often verbally outdue to such answers.
Sometimes I am in temptation to guess such experiments that I try the next stronger “pronounced” drug: tramal, tilidine, xanax codein, etc., but in this case the questioner has his own testimonies already behind him. He seems to be one of the Naloxon candidates.
I also think that is more general than specific. To advise someone to deliberately expose a danger has nix to do with safer use. If you’re insecure about this, you’ll leave it all. Point out.
Dxm is mainly metabolized via cyp2d6.
Grapefruit juice is an inhibitor of cyp3a4,cyp1a2 as well as, inter alia, cyp2d6.
These are enzymes that are important for the metabolism path of (non-body) substances.
By the inhibition of 2d6 by the juice, the degradation of dxm is delayed/prevented. What is equivalent to work amplification, but also with a higher risk of overdose
Thank you
I generally recommend mixing dxm with something like that. The dosage for a “noise” is often higher than the therapeutic dose. This can increase the side effects considerably.
Can’t you just run slowly? How much does the increase in active substance vary?
That’s the problem. No one can tell you exactly what your enzymatic situation looks like. Consequently, the effective amplification can also deviate extremely.
The example of other media:
If betablockers (heart media) are taken with orange or grapefruit juice, this can lead to death from an increased drop in blood pressure.
Before you mix anything, you should take clean first. If it must be absolutely. In my world, it doesn’t have to. That’s n medi, no smartie