Chemical reaction, what's coming?
The question is what happens to it. I thought the ether, CH3Br, and Mg were used to make a Grignard reagent. That would explain all the reagents at "1."
Then there's another reaction where the CH3 of the Grignard reagent is replaced with HO by adding H2O. Then the reagents would be compatible, but the reactant wouldn't be present.
Or one can use the Grignard reagent to open the epoxide by adding CH3BrMg and ether to the reactant to open it, but then the water reagent would be missing.
Is there a way to do a reaction that includes the reactant and all reagents?
(1 votes)
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The epoxide ring is preferably attacked by the nucleophile CH3-Mg.Br for steric reasons at the lowest substituted carbon. A secondary alcohol results after step 2 (hydrolysis).
cyclohexyl-CH(OH)-C2H5
Thank you.
Step 2 is simply the aqueous workup after the Gringard reaction. This is quite common in inorganic auxiliaries anyway!
Have you not done an OC practice yet?
No, I haven’t, thank you for the answer!